{"id":700,"date":"2016-11-21T20:50:06","date_gmt":"2016-11-21T11:50:06","guid":{"rendered":"http:\/\/minna-hiroba.com\/iryou\/?p=700"},"modified":"2016-11-21T20:50:06","modified_gmt":"2016-11-21T11:50:06","slug":"%e3%83%93%e3%82%bf%e3%83%9f%e3%83%b3%ef%bd%83%e3%80%80%e6%8a%95%e4%b8%8e%e3%80%80%e7%99%8c%e6%b2%bb%e7%99%82","status":"publish","type":"post","link":"https:\/\/naosuzo-mystyle.com\/tounyou\/2016\/11\/21\/%e3%83%93%e3%82%bf%e3%83%9f%e3%83%b3%ef%bd%83%e3%80%80%e6%8a%95%e4%b8%8e%e3%80%80%e7%99%8c%e6%b2%bb%e7%99%82\/","title":{"rendered":"\u30d3\u30bf\u30df\u30f3\uff23\u3000\u6295\u4e0e\u3000\u764c\u6cbb\u7642"},"content":{"rendered":"<p>\u304c\u3093\u306b\u5bfe\u3059\u308b\u9ad8\u6fc3\u5ea6\u30d3\u30bf\u30df\u30f3C\u70b9\u6ef4\u7642\u6cd5<br \/>\n<span class=\"icon_h3\">\u30d3\u30bf\u30df\u30f3C\u306f\u304c\u3093\u306b\u52b9\u304f<\/span><\/p>\n<div class=\"thum_right\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.cancerclinic.jp\/cancer_treatments\/images\/img_vitamin_c.jpg\" alt=\"\u9ad8\u6fc3\u5ea6\u30d3\u30bf\u30df\u30f3C\u70b9\u6ef4\u7642\u6cd5 \u70b9\u6ef4\u30a4\u30e1\u30fc\u30b8\" width=\"260\" height=\"300\" \/><\/div>\n<p>\u304c\u3093\u306b\u5bfe\u3059\u308b\u9ad8\u6fc3\u5ea6\u30d3\u30bf\u30df\u30f3C\u70b9\u6ef4\u7642\u6cd5\u306f\u3001\u30ce\u30fc\u30d9\u30eb\u8cde\u30922\u5ea6\u53d7\u8cde\u3057\u305f\u30e9\u30a4\u30ca\u30b9\u30fb\u30dd\u30fc\u30ea\u30f3\u30b0\u535a\u58eb\u3089\u304c\u3001\u81ea\u3089\u306e\u30c7\u30fc\u30bf\u304b\u3089\u3001\u300c\u30d3\u30bf\u30df\u30f3C\u3067\u304c\u3093\u304c\u6cbb\u308b\u300d\u3053\u3068\u3092\u767a\u8868\u3057\u305f1970\u5e74\u4ee3\u304b\u3089\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3059\u3050\u3055\u307e\u5426\u5b9a\u7684\u306a\u8ad6\u6587\u304c\u7d9a\u3051\u3066\u767a\u8868\u3055\u308c\u305f\u305f\u3081\u3001\u305d\u306e\u5f8c\u306f\u3042\u307e\u308a\u6ce8\u76ee\u3055\u308c\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3068\u3053\u308d\u304c\u30012005\u5e74\u306b\u30a2\u30e1\u30ea\u30ab\u56fd\u7acb\u885b\u751f\u7814\u7a76\u6240\uff08National Institute of Hearth: NIH\uff09\u304b\u3089\u3001\u30d3\u30bf\u30df\u30f3C\u304c\u304c\u3093\u7d30\u80de\u306b\u52b9\u304f\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u95a2\u3059\u308b\u8ad6\u65871)\u304c\u767a\u8868\u3055\u308c\u3066\u4ee5\u6765\u3001\u518d\u3073\u6ce8\u76ee\u3055\u308c\u3001\u7c73\u56fd\u306e\u5927\u5b66\u75c5\u9662\u306a\u3069\u3067\u81e8\u5e8a\u8a66\u9a13\u304c\u884c\u308f\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u65e5\u672c\u3067\u3082\u30af\u30ea\u30cb\u30c3\u30af\u9662\u9577\u306e\u6fa4\u767b\u96c5\u4e00\u304c\u975e\u5e38\u52e4\u8b1b\u5e2b\u3092\u52e4\u3081\u308b\u6771\u6d77\u5927\u5b66\u8840\u6db2\u816b\u760d\u5185\u79d1\u3067\u3001\u57fa\u790e\u7684\u30fb\u81e8\u5e8a\u7684\u7814\u7a76\u304c\u884c\u308f\u308c\u3066\u304a\u308a\u3001\u30d3\u30bf\u30df\u30f3C\u306e\u6297\u816b\u760d\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3066\u304a\u308a\u307e\u3059\u3002<br \/>\n&nbsp;<\/p>\n<h3 id=\"p02\"><span class=\"icon_h3\">\u304c\u3093\u7d30\u80de\u3060\u3051\u3092\u9078\u629e\u7684\u306b\u653b\u6483\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0<\/span><\/h3>\n<p>NIH\u306e\u8ad6\u6587\u3067\u306f\u3001\u6297\u9178\u5316\u7269\u8cea\u3067\u3042\u308b\u30d3\u30bf\u30df\u30f3C\u306f\u3001\u3080\u3057\u308d\u5f37\u3044\u9178\u5316\u4f5c\u7528\u3092\u8a98\u5c0e\u3057\u304c\u3093\u7d30\u80de\u3092\u6bba\u3059\u3053\u3068\u3001\u3055\u3089\u306b\u3001\u6b63\u5e38\u7d30\u80de\u306b\u306f\u4f55\u306e\u30c0\u30e1\u30fc\u30b8\u3082\u4e0e\u3048\u306a\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n\u30d3\u30bf\u30df\u30f3C\u304c\u9ad8\u6fc3\u5ea6\u306b\u306a\u308b\u3068\u3001\u5f37\u3044\u9178\u5316\u4f5c\u7528\u3092\u3082\u3064\u30d2\u30c9\u30ed\u30ad\u30b7\u30e9\u30b8\u30ab\u30eb\u3092\u8a98\u3057\u307e\u3059\u3002\u304c\u3093\u7d30\u80de\u306f\u3001\u30ab\u30bf\u30e9\u30fc\u30bc\uff08\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u30e9\u30b8\u30ab\u30eb\u3092\u4e2d\u548c\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u9175\u7d20\uff09\u6d3b\u6027\u304c\u4f4e\u3044\u3068\u3044\u3046\u7279\u5fb4\u304c\u3042\u308a\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u30e9\u30b8\u30ab\u30eb\u306b\u653b\u6483\u3055\u308c\u3084\u3059\u3044\u74b0\u5883\u306b\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3001\u6b63\u5e38\u7d30\u80de\u306f\u30ab\u30bf\u30e9\u30fc\u30bc\u6d3b\u6027\u304c\u9ad8\u304f\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u30e9\u30b8\u30ab\u30eb\u306b\u3088\u308b\u60aa\u5f71\u97ff\u3092\u53d7\u3051\u306b\u304f\u3044\u306e\u3067\u3059\u3002<br \/>\n\u307e\u305f\u3001\u304c\u3093\u7d30\u80de\u306f\u30d6\u30c9\u30a6\u7cd6\u3092\u53d6\u308a\u8fbc\u307f\u3084\u3059\u3044\u3068\u3044\u3046\u6027\u8cea\u304c\u3042\u308a\u3001\u30d6\u30c9\u30a6\u7cd6\u3068\u69cb\u9020\u304c\u4f3c\u3066\u3044\u308b\u30d3\u30bf\u30df\u30f3C\u306f\u304c\u3093\u7d30\u80de\u306b\u53d6\u308a\u8fbc\u307e\u308c\u3084\u3059\u3044\u3068\u3044\u3046\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u304c\u3093\u7d30\u80de\u306b\u306f\u6b63\u5e38\u7d30\u80de\u3088\u308a\u591a\u304f\u306e\u30d2\u30c9\u30ed\u30ad\u30b7\u30e9\u30b8\u30ab\u30eb\u304c\u767a\u751f\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u304c\u3001\u30d3\u30bf\u30df\u30f3C\u7642\u6cd5\u304c\u3001\u304c\u3093\u7d30\u80de\u306b\u7279\u7570\u7684\u306b\u50cd\u304f\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3042\u308a\u3001\u5b9f\u969b\u306b\u306f\u3001\u30d3\u30bf\u30df\u30f3C\u306e\u8840\u6db2\u4e2d\u6fc3\u5ea6\u304c400mg\/dl(22^23mM)\u524d\u5f8c\u306b\u9054\u3059\u308b\u3068\u5f37\u3044\u6297\u816b\u760d\u52b9\u679c\u304c\u767a\u63ee\u3055\u308c\u308b\u306e\u3067\u3001\u9ad8\u6fc3\u5ea6\u30d3\u30bf\u30df\u30f3C\u70b9\u6ef4\u7642\u6cd5\u3067\u306f\u3053\u306e\u6fc3\u5ea6\u3092\u76ee\u6a19\u3068\u3057\u307e\u3059\u3002<br \/>\n<!--more--><br \/>\n\u30d3\u30bf\u30df\u30f3C\u304c\u5f79\u5272\u3092\u679c\u305f\u3059\u305f\u3081\u306b\u306f\u3001\u8840\u6db2\u4e2d\u306e\u6fc3\u5ea6\u304c\u91cd\u8981\u3067\u3059\u3002\u76ee\u6a19\u3068\u3059\u308b400mg\/dl\u306f\u7d4c\u53e3\u6295\u4e0e\u3067\u306f\u5230\u9054\u3059\u308b\u3053\u3068\u306e\u3067\u304d\u306a\u3044\u6fc3\u5ea6\u3067\u3042\u308a\u3001\u30d3\u30bf\u30df\u30f3C\u7642\u6cd5\u304c\u70b9\u6ef4\u3067\u884c\u308f\u308c\u308b\u306e\u306f\u305d\u306e\u305f\u3081\u3067\u3001\u5b9f\u969b\u306b\u306f\u3001\u70b9\u6ef4\u7d42\u4e86\u76f4\u5f8c\u306b\u63a1\u8840\u3092\u3057\u3066\u3001\u8840\u6db2\u4e2d\u6fc3\u5ea6\u3092\u8a55\u4fa1\u3057\u307e\u3059\u3002\u30d3\u30bf\u30df\u30f3C\u306e\u8840\u4e2d\u6fc3\u5ea6\u306b\u306f\u3001\u60a3\u8005\u3055\u3093\u306e\u5168\u8eab\u72b6\u614b\u3084\u304c\u3093\u306e\u62e1\u304c\u308a\u3001\u6804\u990a\u72b6\u614b\u3001\u55ab\u7159\u306e\u6709\u7121\u306a\u3069\u3055\u307e\u3056\u307e\u306a\u8981\u7d20\u304c\u5f71\u97ff\u3057\u307e\u3059\u3002<\/p>\n<h3 id=\"p03\"><span class=\"icon_h3\">\u8840\u7ba1\u65b0\u751f\u3092\u6291\u5236\u3059\u308b\u65b0\u305f\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u767a\u898b<\/span><\/h3>\n<p>\u30af\u30ea\u30cb\u30c3\u30af\u9662\u9577\u306e\u6fa4\u767b\u96c5\u4e00\u306f\u3001\u975e\u5e38\u52e4\u8b1b\u5e2b\u3068\u3057\u3066\u6240\u5c5e\u3059\u308b\u6771\u6d77\u5927\u5b66\u533b\u5b66\u90e8\u8840\u6db2\u30fb\u816b\u760d\u5185\u79d1\u3067\u3001\u540c\u5927\u3001\u5ddd\u7530\u6d69\u5fd7\u51c6\u6559\u6388\u3089\u3068\u5171\u306b\u9ad8\u6fc3\u5ea6\u30d3\u30bf\u30df\u30f3C\u304c\u8840\u7ba1\u65b0\u751f\u3092\u6291\u5236\u3059\u308b\u3068\u3044\u3046\u65b0\u3057\u3044\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002<br \/>\n\u672c\u7814\u7a76\u6210\u679c\u306f\u3001<a href=\"http:\/\/www.cancerclinic.jp\/cancer_treatments\/vitamin_c_instillation.html#article\"><u><span style=\"color: #0066cc;\">\u7c73\u56fd\u306e\u79d1\u5b66\u8a8c\u300cPLOS ONE\uff08\u30d7\u30ed\u30b9\u30fb\u30ef\u30f3\uff09\u300d\u306b\u3001\u73fe\u5730\u6642\u95932013\u5e744\u670823\u65e5\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u82f1\u6587\uff09\u3002<\/span><\/u><\/a><br \/>\n\u4eca\u56de\u306e\u7814\u7a76\u306f\u3001\u30d2\u30c8\u306e\u767d\u8840\u75c5\u7d30\u80de\u306b\u3064\u3044\u3066\u884c\u308f\u308c\u3001\u9ad8\u6fc3\u5ea6\u30d3\u30bf\u30df\u30f3C\u304c\u8840\u7ba1\u65b0\u751f\u3092\u6291\u3048\u308b\u50cd\u304d\u3092\u3082\u3061\u3001\u305d\u306e\u3053\u3068\u306b\u3088\u3063\u3066\u767d\u8840\u75c5\u7d30\u80de\u306e\u5897\u6b96\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u3001\u30de\u30a6\u30b9\u3092\u4f7f\u3063\u305f\u52d5\u7269\u5b9f\u9a13\u3067\u65b0\u305f\u306b\u89e3\u660e\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u8840\u7ba1\u65b0\u751f\u306b\u95a2\u308f\u308b\u5206\u5b50\uff08VEGF\uff09\u3092\u6291\u5236\u3059\u308b\u300cHIF1\u03b1\u300d\u3068\u3044\u3046\u5206\u5b50\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u7d50\u679c\u7684\u306b\u8840\u7ba1\u65b0\u751f\u3092\u963b\u5bb3\u3057\u3001\u767d\u8840\u75c5\u306e\u9032\u884c\u3092\u6291\u5236\u3059\u308b\u3068\u3044\u3046\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3059\u3002<br \/>\n\u672c\u7814\u7a76\u306e\u6210\u679c\u306f\u3001\u9ad8\u6fc3\u5ea6\u30d3\u30bf\u30df\u30f3C\u306e\u65b0\u305f\u306a\u6297\u816b\u760d\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u767a\u898b\u3068\u3057\u3066\u4eca\u5f8c\u6ce8\u76ee\u3055\u308c\u307e\u3059\u3002<\/p>\n<div id=\"article\" class=\"frame-bg\">\n<strong class=\"font12\">\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u7c73\u56fd\u306e\u79d1\u5b66\u8a8c\u300cPLOS ONE\uff08\u30d7\u30ed\u30b9\u30fb\u30ef\u30f3\uff09\u300d\u306b\u3001\u73fe\u5730\u6642\u95932013\u5e744\u670823\u65e5\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\uff08\u82f1\u6587\uff09\u3002<\/strong><\/p>\n<p class=\"font12\"><strong><a class=\"externalLink\" href=\"http:\/\/www.plosone.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pone.0062717\" target=\"_blank\"><u><span style=\"color: #0066cc;\">\u300eHigh Concentrations of L-Ascorbic Acid Specifically Inhibit the Growth of Human Leukemic Cells via Downregulation of HIF-1\u03b1 Transcription\u300f<\/span><\/u><\/a><\/strong><br \/>\n<a class=\"externalLink\" href=\"http:\/\/www.plosone.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pone.0062717\" target=\"_blank\"><u><span style=\"color: #0066cc;\">http:\/\/www.plosone.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pone.0062717<\/span><\/u><\/a><\/p>\n<\/div>\n<h3><span class=\"icon_h3\">\u9ad8\u6fc3\u5ea6\u30d3\u30bf\u30df\u30f3C\u70b9\u6ef4\u7642\u6cd5\u3067\u671f\u5f85\u3055\u308c\u308b\u52b9\u679c<\/span><\/h3>\n<p><strong>\u304c\u3093\u7d30\u80de\u3092\u6b7b\u6ec5\u3055\u305b\u308b\u52b9\u679c<\/strong><br 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