{"id":1897,"date":"2017-01-17T15:02:38","date_gmt":"2017-01-17T06:02:38","guid":{"rendered":"http:\/\/naosuzo.net\/?p=1897"},"modified":"2019-07-30T09:00:03","modified_gmt":"2019-07-30T00:00:03","slug":"su%e8%96%ac%ef%bc%88%e3%82%b9%e3%83%ab%e3%83%9b%e3%83%8b%e3%83%ab%e5%b0%bf%e7%b4%a0%e8%96%ac%ef%bc%89%e3%81%ae%e4%bd%9c%e7%94%a8%e6%a9%9f%e5%ba%8f","status":"publish","type":"post","link":"http:\/\/naosuzo-mystyle.com\/tounyoubyou\/?p=1897","title":{"rendered":"\u5371\u967a\u306aSU\u85ac\uff08\u30b9\u30eb\u30db\u30cb\u30eb\u5c3f\u7d20\u85ac\uff09\u3084\u3081\u7cd6\u8cea\u5236\u9650\u3067\uff01"},"content":{"rendered":"<p>\u7cd6\u5c3f\u75c5\u6027\u814e\u75c7\u306f\u7cd6\u5c3f\u75c5\u306b\u3064\u304d\u3082\u306e\u306e\u8840\u7cd6\u5024\u964d\u4e0b\u4fc3\u9032\u5264\u3067\u3059\u3002\u308f\u305f\u3057\u306f\u3001\u3053\u308c\u3067\u814e\u81d3\u6a5f\u80fd\u60aa\u5316\u306b\u5f80\u751f\u3057\u3066\u3044\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u306b\u306a\u3063\u3066\u30011\u5e74\u304f\u3089\u3044\u305f\u3063\u305f\u3053\u308d\u3001\u6025\u306b\u300c\u814e\u900f\u6790\u306e\u8b1b\u7fd2\u53d7\u3051\u307e\u305b\u3093\u304b\uff1f\u300d\u3068\u6253\u8a3a\u3055\u308c\u306a\u3093\u306e\u3053\u3068\u304b\u3001\u89e3\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u691c\u67fb\u7d50\u679c\u307f\u308b\u3068\u3001\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u306e\u6570\u5024\u304c\u3042\u304c\u308a\u3001\u3042\u3042\u3001\u305d\u3046\u306a\u3093\u3060\uff1f\u3068\u3001\u610f\u5473\u304c\u308f\u304b\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<br \/>\n\u3044\u308d\u3044\u308d\u8abf\u3079\u308b\u3046\u3061\u3001\u30a4\u30f3\u30b7\u30e5\u30ea\u30f3\u6ce8\u5c04\u304c\u539f\u56e0\u304b\u306a\u3042\u3068\u3057\u3089\u3079\u307e\u3057\u305f\u304c\u3001\u5224\u660e\u305b\u305a\u3001SU\u5264\u306e\u30b0\u30e9\u30af\u30c6\u30a3\u30d6\u9320\u306b\u884c\u304d\u3064\u304d\u3001\u7d50\u679c\u7684\u306b\u30a4\u30f3\u30b7\u30e5\u30ea\u30f3\u6ce8\u5c04\u3082\u85ac\u3082\u3084\u3081\u3001\u8840\u7cd6\u5024\u3082\u3084\u3084\u6b63\u5e38\u306b\u306a\u308a\u307e\u3057\u305f\u3002\uff13\u304b\u6708\u3067\u306a\u304a\u3057\u307e\u3057\u305f\u3002<br \/>\n\u307e\u3055\u304b\u30a4\u30f3\u30b7\u30e5\u30ea\u30f3\u4fc3\u9032\u5264\u306e\u30b0\u30e9\u30af\u30c6\u30a3\u30d6\u9320\u304c\u814e\u900f\u6790\u306e\u8981\u56e0\u3068\u306f\u3001\u601d\u3044\u3082\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u307b\u3068\u3093\u3069\u306e\u304b\u305f\u304c\u3001\u814e\u900f\u6790\u306e\u4e0d\u5b89\u306b\u304a\u3073\u3048\u307e\u3059\u3002<br \/>\n\u3044\u304b\u306b\u85ac\u306e\u6016\u3055\u304c\u3001\u7406\u89e3\u3067\u304d\u307e\u3057\u305f\u3002\u7814\u7a76\u3057\u3066\u307f\u3066\u304f\u3060\u3055\u3044\u3002<br \/>\n<!--more--><\/p>\n<p>\uff33\uff35\u85ac\u306f\u300c\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\u85ac\u300d\u306b\u5206\u985e\u3055\u308c\u3001\u81b5\u81d3\u306e\u03b2\u7d30\u80de\u3092\u523a\u6fc0\u3057\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u3092\u4fc3\u9032\u3055\u305b\u307e\u3059\u3002<br \/>\n\u8fd1\u5e74\u767b\u5834\u3057\u305fDPP-\u2163\u963b\u5bb3\u85ac\u306b\u3088\u308a\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306e\u9078\u629e\u80a2\u304c\u5e83\u304c\u308a\u3001\u4ee5\u524d\u3088\u308a\u3082SU\u85ac\u306e\u4f7f\u7528\u983b\u5ea6\u306f\u5c11\u306a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3057\u304b\u3057\u306a\u304c\u3089\u3001SU\u85ac\u304c\u793a\u3059\u5f37\u529b\u306a\u8840\u7cd6\u964d\u4e0b\u4f5c\u7528\u306f\u3001\u73fe\u5728\u306e\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306b\u304a\u3044\u3066\u3082\u91cd\u8981\u306a\u4f4d\u7f6e\u3065\u3051\u306b\u3042\u308a\u307e\u3059\u3002<br \/>\n\u4eca\u56de\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u6a5f\u69cb\u304b\u3089SU\u85ac\u306e\u4f5c\u7528\u6a5f\u5e8f\u3001\u5404\u85ac\u5264\u306e\u9055\u3044\u306a\u3069\u306b\u3064\u3044\u3066\u5fb9\u5e95\u30de\u30b9\u30bf\u30fc\u3057\u3066\u3044\u304d\u307e\u3057\u3087\u3046\uff01<br \/>\n<!--more--><\/p>\n<div id=\"toc_container\" class=\"no_bullets\">\n<p class=\"toc_title\">\u76ee\u6b21 <span class=\"toc_toggle\">[<a href=\"http:\/\/next-pharmacist.net\/archives\/4175#\"><u><span style=\"color: #0066cc;\">\u975e\u8868\u793a<\/span><\/u><\/a>]<\/span><\/p>\n<ul class=\"toc_list\">\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#i\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_1\">1<\/span> \u307e\u305a\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u304b\u3089\u5b66\u307c\u3046\uff01<\/span><\/u><\/a>\n<ul>\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#KATP\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_2\">1.1<\/span> KATP\u30c1\u30e3\u30cd\u30eb\u3068\u306f<\/span><\/u><\/a><\/li>\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#i-2\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_2\">1.2<\/span> \u30b0\u30eb\u30b3\u30fc\u30b9\u306b\u3088\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc<\/span><\/u><\/a><\/li>\n<\/ul>\n<\/li>\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#i-3\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_1\">2<\/span> \uff33\uff35\u85ac\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u30e1\u30ab\u30cb\u30ba\u30e0<\/span><\/u><\/a>\n<ul>\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#KATP-2\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_2\">2.1<\/span> \u5404\u81d3\u5668\u306eKATP\u30c1\u30e3\u30cd\u30eb\u306e\u6a5f\u80fd<\/span><\/u><\/a><\/li>\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#SUR2A\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_2\">2.2<\/span> SUR2A\u306b\u3082\u7d50\u5408\u3059\u308b\u3068\uff65\uff65\uff65\uff1f<\/span><\/u><\/a><\/li>\n<\/ul>\n<\/li>\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#SU\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_1\">3<\/span> SU\u85ac\u306e\u7a2e\u985e\u3068\u7279\u5fb4<\/span><\/u><\/a>\n<ul>\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#SU-2\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_2\">3.1<\/span> \u7b2c\uff11\u4e16\u4ee3SU\u85ac<\/span><\/u><\/a><\/li>\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#SU-3\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_2\">3.2<\/span> \u7b2c\uff12\u4e16\u4ee3SU\u85ac<\/span><\/u><\/a><\/li>\n<li><a href=\"http:\/\/next-pharmacist.net\/archives\/4175#SU-4\"><u><span style=\"color: #0066cc;\"><span class=\"toc_number toc_depth_2\">3.3<\/span> \u7b2c\uff13\u4e16\u4ee3SU\u85ac<\/span><\/u><\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<h2><span id=\"i\">\u307e\u305a\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u304b\u3089\u5b66\u307c\u3046\uff01<\/span><\/h2>\n<p>\u81b5\u03b2\u7d30\u80de\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u300c\u30a4\u30f3\u30b9\u30ea\u30f3\u300d\u306f\u3001\u8840\u7cd6\u5024\u306e\u6052\u5e38\u6027\u306e\u7dad\u6301\u306b\u4e0d\u53ef\u6b20\u3067\u3059\u3002<br \/>\n\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u30b0\u30eb\u30b3\u30fc\u30b9\u306b\u3088\u308a\u5206\u6ccc\u304c\u5236\u5fa1\u3055\u308c\u3066\u304a\u308a\u3001\u73fe\u5728\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u4e3b\u8981\u306a\u7d4c\u8def\u306fK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u3092\u4ecb\u3059\u308b\u7d4c\u8def\u3067\u3059\u3002<br \/>\n\u82f1\u8a9e\u3067\u306f\u3001K<sub><span style=\"font-size: small;\">ATP<\/span><\/sub> channel-dependent pathway\u3001\u307e\u305f\u306f triggering pathway\u3068\u3044\u308f\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3053\u306e\u7d4c\u8def\u304c\u73fe\u5728\u306e\u6cbb\u7642\u85ac\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u3082\u306a\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\n\u306a\u306e\u3067\u3001\u307e\u305a\u306f\u3053\u306eK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u3092\u4ecb\u3057\u305f\u7d4c\u8def\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u307f\u3066\u3044\u304d\u307e\u3057\u3087\u3046\uff01<\/p>\n<h3><span id=\"KATP\">K<sub><span style=\"font-size: medium;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u3068\u306f<\/span><\/h3>\n<p>\u306f\u3058\u3081\u306b\u3001K<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306e\u69cb\u9020\u304b\u3089\u307f\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<br \/>\nK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306f\uff12\u7a2e\u985e\u306e\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u304b\u3089\u306a\u308a\u307e\u3059\u3002\u7c21\u5358\u306b\u3044\u3046\u3068\u3001\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u3068\u306f\u30bf\u30f3\u30d1\u30af\u5168\u4f53\u3092\u69cb\u6210\u3059\u308b\u5927\u304d\u306a\u90e8\u54c1\u30fb\u584a\u306e\u3053\u3068\u3067\u3059\u3002<br \/>\n\u56f3\u3092\u307f\u305f\u65b9\u304c\u306f\u3084\u3044\uff01\u3067\u3059\u3088\u306d\u3002\u30a4\u30e1\u30fc\u30b8\u306f\u3053\u3093\u306a\u5f62\u3067\u3059\u2193<br \/>\n<a href=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-Katp.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4183\" src=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-Katp.jpg\" sizes=\"auto, (max-width: 259px) 100vw, 259px\" srcset=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-Katp.jpg 259w, http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-Katp-243x300.jpg 243w\" alt=\"s-Katp\" width=\"259\" height=\"320\" \/><\/a><br \/>\nSUR1\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\uff1aABC\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u30b9\u30fc\u30d1\u30fc\u30d5\u30a1\u30df\u30ea\u30fc\u306b\u5c5e\u3057\u3001SU\u85ac\u306a\u3069\u69d8\u3005\u306a\u85ac\u5264\u3068\u306e\u7d50\u5408\u90e8\u4f4d\u3092\u3082\u3064<br \/>\nKir6.2\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\uff1aK+\u30c1\u30e3\u30cd\u30eb\u306b\u5c5e\u3057\u3001\u30c1\u30e3\u30cd\u30eb\u30dd\u30a2\u3092\u5f62\u6210\u3059\u308b<br \/>\n\u3053\u306e\uff12\u3064\u306e\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u304c4\u3064\u305a\u3064\u3001\u5408\u8a08\uff18\u3064\u304c\u7d50\u5408\u3057\u305f\u30d8\u30c6\u30ed8\u91cf\u4f53\u69cb\u9020\u306b\u306a\u3063\u3066\u304a\u308a\u3001\u30c1\u30e3\u30cd\u30eb\u306e\u6a5f\u80fd\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<br \/>\n\u3053\u3046\u3044\u3046K<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u304c\u81b5\u03b2\u7d30\u80de\u306b\u306f\u3042\u308b\u3093\u3060\u3068\u3044\u3046\u3053\u3068\u3092\u30a4\u30e1\u30fc\u30b8\u3057\u3066\u304a\u3044\u3066\u3001\u6b21\u306b\u81b5\u03b2\u7d30\u80de\u306e\u7c21\u7565\u56f3\u3092\u307f\u3066\u307f\u307e\u3057\u3087\u3046\u3002<br \/>\n<a href=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-su.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4185\" src=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-su.jpg\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" srcset=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-su.jpg 600w, http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-su-300x140.jpg 300w, http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-su-320x149.jpg 320w\" alt=\"s-su\" width=\"600\" height=\"280\" \/><\/a><br \/>\n\u4f55\u3082\u523a\u6fc0\u304c\u306a\u3044\u72b6\u614b\u3067\u306f\u3001\u81b5\u03b2\u7d30\u80de\u306eK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306f\u3042\u308b\u4e00\u5b9a\u306e\u983b\u5ea6\uff08\uff1d\u958b\u53e3\u7387\uff09\u3067\u30c1\u30e3\u30cd\u30eb\u306e\u958b\u53e3\u3068\u9589\u9396\u3092\u7e70\u308a\u8fd4\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3053\u306e\u6a5f\u80fd\u306b\u3088\u308a\u3001\u7d30\u80de\u5185\u304b\u3089\u7d30\u80de\u5916\u3078\u30ab\u30ea\u30a6\u30e0\u30a4\u30aa\u30f3\uff08K<sup><span style=\"font-size: small;\">+<\/span><\/sup>\uff09\u304c\u4e00\u5b9a\u91cf\u653e\u51fa\u3055\u308c\u308b\u3053\u3068\u3067\u7d30\u80de\u5185\u30fb\u5916\u306eK<sup><span style=\"font-size: small;\">+<\/span><\/sup>\u6fc3\u5ea6\u5e73\u8861\u304c\u4fdd\u305f\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u4f55\u3089\u304b\u306e\u523a\u6fc0\u304c\u52a0\u308f\u3063\u3066\u3001\u3053\u306e\u5747\u8861\u72b6\u614b\u304c\u5d29\u308c\u308b\u3053\u3068\u3067\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u5206\u6ccc\u3055\u308c\u307e\u3059\u3002<br \/>\n\u3067\u306f\u3001\u56f3\u3092\u307f\u306a\u304c\u3089\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u5206\u6ccc\u3055\u308c\u308b\u307e\u3067\u306e\u7d4c\u8def\u3092\u9806\u306b\u8ffd\u3063\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n<h3><span id=\"i-2\">\u30b0\u30eb\u30b3\u30fc\u30b9\u306b\u3088\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc<\/span><\/h3>\n<p>\u2460\u30b0\u30eb\u30b3\u30fc\u30b9\u304c\u7cd6\u8f38\u9001\u62c5\u4f53\uff08GLUT2\uff09\u3092\u4ecb\u3057\u3066\u7d30\u80de\u5916\u304b\u3089\u7d30\u80de\u5185\u306b\u53d6\u308a\u8fbc\u307e\u308c\u307e\u3059\u3002<br \/>\n\u2461\u89e3\u7cd6\u7cfb\u304a\u3088\u3073\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u5185\u3067\u306e\u9178\u5316\u7684\u30ea\u30f3\u9178\u5316\u306b\u3088\u308aATP\u304c\u7523\u751f\u3055\u308c\u307e\u3059\u3002\uff08\u56f3\u306e\u300c\u4ee3\u8b1d\u300d\u306e\u904e\u7a0b\uff09<br \/>\n\u2462\u7d50\u679c\u7684\u306b\u7d30\u80de\u5185\u306eATP\u6fc3\u5ea6\u304c\u4e0a\u304c\u308a\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u751f\u7406\u7684\u6761\u4ef6\u3067\u306f\u7d30\u80de\u5185\u306eADP\u6fc3\u5ea6\u306f\u307b\u3068\u3093\u3069\u5909\u5316\u3057\u306a\u3044\u306e\u3067\u3001\u300cATP\/ADP\u6bd4\u300d\u304c\u5897\u5927\u3057\u307e\u3059\u3002<br \/>\n\u2463ATP\/ADP\u6bd4\u306e\u5897\u52a0\u306b\u3088\u308aK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306e\u958b\u53e3\u7387\u304c\u4f4e\u4e0b\u3057\u307e\u3059\u3002<br \/>\n\u2464\u7d30\u80de\u5916\u3078\u306eK<sup><span style=\"font-size: small;\">+<\/span><\/sup>\u6392\u6cc4\u304c\u6ede\u308a\u3001\u7d30\u80de\u5185\u306bK<sup><span style=\"font-size: small;\">+<\/span><\/sup>\u304c\u6e9c\u307e\u308b\u3053\u3068\u3067\u7d30\u80de\u819c\u306e\u96fb\u4f4d\uff08\u9759\u6b62\u819c\u96fb\u4f4d\uff1a-70mV\uff09\u304c\u4e0a\u6607\u3057\u3066\u3044\u304d\u307e\u3059\u3002<br \/>\n\u2465\u3042\u308b\u4e00\u5b9a\u306e\u96fb\u4f4d\uff08-40mV\u524d\u5f8c\uff09\u306b\u307e\u3067\u819c\u96fb\u4f4d\u304c\u4e0a\u6607\u3059\u308b\u3068\u3001\u305d\u306e\u523a\u6fc0\u306b\u53cd\u5fdc\u3057\u3066\u96fb\u4f4d\u4f9d\u5b58\u6027Ca<sup>2+<\/sup>\u30c1\u30e3\u30cd\u30eb\uff08VDCC\uff09\u304c\u958b\u53e3\u3057\u307e\u3059\u3002<br \/>\n\u2466\u3082\u3068\u3082\u3068\u7d30\u80de\u5185\u3068\u7d30\u80de\u5916\u306eCa\u6fc3\u5ea6\u306b\u306f\u975e\u5e38\u306b\u5927\u304d\u306a\u5dee\uff08\u7d30\u80de\u5185\uff1a\u7d040.0001mM\u3001\u7d30\u80de\u5916\uff1a\u7d042mM\uff09\u304c\u3042\u308b\u305f\u3081\u306b\u3001VDCC\u304c\u958b\u53e3\u3059\u308b\u3068\u7d30\u80de\u5916\u304b\u3089\u7d30\u80de\u5185\u306bCa2+\u304c\u6d41\u5165\u3057\u307e\u3059\u3002<br \/>\n\u2467\u7d30\u80de\u5185\u3078\u306eCa<sup><span style=\"font-size: small;\">2+<\/span><\/sup>\u6d41\u5165\u523a\u6fc0\u306b\u3088\u308a\u3001\u7d30\u80de\u5185\u306b\u3042\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u9846\u7c92\u304c\u7d30\u80de\u819c\u306b\u878d\u5408\u3057\u3066\u9846\u7c92\u4e2d\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u8840\u4e2d\u306b\u653e\u51fa\u3055\u308c\u307e\u3059\u3002<\/p>\n<hr \/>\n<p>\u4ee5\u4e0a\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u306b\u3088\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u5927\u307e\u304b\u306a\u6d41\u308c\u306b\u306a\u308a\u307e\u3059\u3002<br \/>\n\u3053\u3053\u3067\u6c17\u3065\u304f\u3053\u3068\u306f\u3001K<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306b\u306f\u91cd\u8981\u306a\uff12\u3064\u306e\u5f79\u5272\u304c\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\uff01<br \/>\n\u3072\u3068\u3064\u304c\u3001\u03b2\u7d30\u80de\u5185\u3067\u306e\u30b0\u30eb\u30b3\u30fc\u30b9\u4ee3\u8b1d\u5909\u5316\u3001\u3064\u307e\u308aATP\/ADP\u6bd4\u3092\u611f\u77e5\u3059\u308b\u300c\u4ee3\u8b1d\u30bb\u30f3\u30b5\u30fc\u300d\u306e\u5f79\u5272\u3067\u3059\u3002<br \/>\n\u3082\u3046\u3072\u3068\u3064\u304c\u3001\u30ab\u30ea\u30a6\u30e0\u30a4\u30aa\u30f3\u306e\u529b\u3092\u501f\u308a\u308b\u3053\u3068\u3067\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u4ee3\u8b1d\u5909\u5316\u3092\u96fb\u6c17\u7684\u4fe1\u53f7\uff08\u03b2\u7d30\u80de\u819c\u306e\u96fb\u4f4d\u5909\u5316\uff09\u306b\u5909\u63db\u3059\u308b\u300c\u4fe1\u53f7\u5909\u63db\u5668\u300d\u306e\u5f79\u5272\u3067\u3059\u3002<br \/>\n\u3053\u308c\u3089\u306e\u6a5f\u80fd\u306b\u3088\u308a\u3001\u5358\u7d14\u306a\u30b0\u30eb\u30b3\u30fc\u30b9\u6fc3\u5ea6\u306e\u5909\u5316\u304b\u3089\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u5206\u6ccc\u3055\u305b\u308b\u307e\u3067\u306e\u6a4b\u6e21\u3057\u3092\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u3002<br \/>\n\u3064\u307e\u308a\u3001K<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306b\u304a\u3044\u3066\u5fc5\u9808\u306e\u9375\u5206\u5b50\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u3002\u305d\u3057\u3066\u3001\u3053\u306eK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u3057\u3066\u3001\u898b\u4e8b\u6210\u529f\u3057\u305f\u306e\u304c\uff33\uff35\u85ac\u3060\u3063\u305f\u306e\u3067\u3059\uff01<\/p>\n<h2><span id=\"i-3\">\uff33\uff35\u85ac\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u30e1\u30ab\u30cb\u30ba\u30e0<\/span><\/h2>\n<p>\u3067\u306f\u672c\u984c\uff01\u3001\u3068\u3044\u3063\u3066\u3082\u307b\u3068\u3093\u3069\u306e\u8aac\u660e\u306f\u3082\u3046\u7d42\u308f\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u304c\u7b11\u3001\uff33\uff35\u85ac\u306e\u4f5c\u7528\u6a5f\u5e8f\u306b\u3064\u3044\u3066\u5c11\u3057\u7d30\u304b\u3044\u3068\u3053\u308d\u307e\u3067\u307f\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<br \/>\n\u307e\u305a\uff33\uff35\u85ac\u3068\u3044\u3046\u547d\u540d\u306f\u3001\u305d\u306e\u85ac\u5264\u69cb\u9020\u306b\u542b\u307e\u308c\u308b\uff33\uff35\u69cb\u9020\u306b\u7531\u6765\u3057\u307e\u3059\u3002<br \/>\n<a href=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sulist.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4210\" src=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sulist.jpg\" sizes=\"auto, (max-width: 650px) 100vw, 650px\" srcset=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sulist.jpg 650w, http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sulist-300x92.jpg 300w, http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sulist-320x98.jpg 320w\" alt=\"s-sulist\" width=\"650\" height=\"200\" \/><br \/>\n<\/a>A\uff1a\u30b0\u30ea\u30d9\u30f3\u30af\u30e9\u30df\u30c9\u3001B\uff1a\u30c8\u30eb\u30d6\u30bf\u30df\u30c9\u3001C\uff1a\u30b0\u30ea\u30e1\u30d4\u30ea\u30c9\u3001D\uff1a\u30b0\u30ea\u30af\u30e9\u30b8\u30c9<br \/>\n\u3053\u306eSU\u69cb\u9020\u304c\u3001K<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u300cSUR1\u300d\u3068\u7279\u7570\u7684\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\nSU\u85ac\u306f\u81b5\u03b2\u7d30\u80de\u819c\u306eSUR1\u306b\u76f4\u63a5\u7d50\u5408\u3057\u3001K<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u3092\u300c\u9589\u53e3\u300d\u3055\u305b\u307e\u3059\u3002<br \/>\n\u3053\u308c\u306b\u3088\u308a\u7d30\u80de\u819c\u306e\u8131\u5206\u6975\u304c\u751f\u3058\u3001\u96fb\u4f4d\u4f9d\u5b58\u6027Ca<sup>2+<\/sup>\u30c1\u30e3\u30cd\u30eb\u304c\u958b\u53e3\u3057\u3001Ca<sup>2+<\/sup>\u30a4\u30aa\u30f3\u304c\u7d30\u80de\u5185\u306b\u6d41\u5165\u3057\u307e\u3059\u3002<br \/>\n\u3053\u3053\u304b\u3089\u5148\u306f\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u306b\u3088\u308b\u751f\u7406\u7684\u306a\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3068\u5171\u901a\u306e\u7d4c\u8def\u306b\u306a\u308a\u307e\u3059\u3002<br \/>\n\u3064\u307e\u308a\u3001ATP\/ADP\u6bd4\u306b\u95a2\u4fc2\u306a\u304f\u3001SU\u85ac\u306fK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306b\u7d50\u5408\u3057\u9589\u53e3\u3055\u305b\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u8a98\u5c0e\u3059\u308b\u306e\u3067\u3059\u3002<br \/>\n\u3010SU\u85ac\u306b\u3088\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u7d4c\u8def\u3011<br \/>\n<a href=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sugrinide.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4219\" src=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sugrinide.jpg\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" srcset=\"http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sugrinide.jpg 600w, http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sugrinide-300x202.jpg 300w, http:\/\/next-pharmacist.net\/wp-content\/uploads\/s-sugrinide-320x215.jpg 320w\" alt=\"s-sugrinide\" width=\"600\" height=\"403\" \/><\/a><br \/>\n\u4e00\u65b9\u3001\u30d9\u30f3\u30ba\u30a2\u30df\u30c9\u69cb\u9020\u3092\u3082\u3064SU\u85ac\u306fSUR1\u3060\u3051\u3067\u306a\u304f\u3001SUR2A\u3084SUR2B\u306a\u3069\u306b\u3082\u7d50\u5408\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3053\u308c\u3089\u306e\u9055\u3044\u304c\u3001\u5404\u85ac\u5264\u306e\u7d44\u7e54\u7279\u7570\u7684\u306a\u85ac\u7406\u4f5c\u7528\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u56e0\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3><span id=\"KATP-2\">\u5404\u81d3\u5668\u306eK<sub><span style=\"font-size: medium;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306e\u6a5f\u80fd<\/span><\/h3>\n<p>Kir\u3001SUR\u306b\u306f\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u304c\u3042\u308a\u3001\u305d\u306e\u5404\u81d3\u5668\u306b\u5b58\u5728\u3059\u308bK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u3067\u306f\u305d\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u7570\u306a\u308a\u307e\u3059\u3002<br \/>\n\u30fb\u81b5\u03b2\u7d30\u80de\uff08Kir6.2\/SUR1\uff09\uff1a\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u8abf\u7bc0<br \/>\n\u30fb\u5fc3\u7b4b\uff08Kir6.2\/SUR2A\uff09\uff1a\u865a\u8840\u6642\u306e\u5fc3\u7b4b\u4fdd\u8b77\u4f5c\u7528<br \/>\n\u30fb\u9aa8\u683c\u7b4b\uff08Kir6.2\/SUR2A\uff09\uff1a\u7cd6\u53d6\u308a\u8fbc\u307f\u8abf\u7bc0\u3001\u75b2\u52b4\u6642\u306e\u9aa8\u683c\u7b4b\u4fdd\u8b77<br \/>\n\u30fb\u5e73\u6ed1\u7b4b\uff08Kir6.2\/SUR2B\uff09\uff1a\u5e73\u6ed1\u7b4b\u306e\u30c8\u30fc\u30cc\u30b9\uff08\u7b4b\u7dca\u5f35\uff09\u8abf\u7bc0<br \/>\n\u30fb\u8840\u7ba1\u5e73\u6ed1\u7b4b\uff08Kir6.1\/SUR2B\uff09\uff1a\u8840\u7ba1\u62e1\u5f35\u30fb\u53ce\u7e2e\u8abf\u7bc0<br \/>\n\u30fb\u5927\u8133\u9ed2\u8cea\uff08Kir6.2\/SUR1\uff09\uff1a\u4f4e\u9178\u7d20\u6642\u306e\u75d9\u6523\u6291\u5236<br \/>\n\u30fb\u8996\u5e8a\u4e0b\u90e8\uff08Kir6.2\/SUR1\uff09\uff1a\u4f4e\u8840\u7cd6\u6642\u306e\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u8abf\u6574<\/p>\n<h3><span id=\"SUR2A\">SUR2A\u306b\u3082\u7d50\u5408\u3059\u308b\u3068\uff65\uff65\uff65\uff1f<\/span><\/h3>\n<p>\u5fc3\u7b4b\u306eK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\uff08SUR6.2\/SUR2A\uff09\u306f\u901a\u5e38\u306f\u307b\u3068\u3093\u3069\u9589\u53e3\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3057\u304b\u3057\u3001\u5fc3\u7b4b\u304c\u865a\u8840\u72b6\u614b\uff08\u5fc3\u7b4b\u5185ATP\u6fc3\u5ea6\u4f4e\u4e0b\uff09\u3068\u306a\u3063\u305f\u3068\u304d\u306b\u306f\u3001K<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u304c\u958b\u53e3\u3059\u308b\u3053\u3068\u3067\u5fc3\u7b4b\u53ce\u7e2e\u529b\u3092\u4f4e\u4e0b\u3055\u305b\u3066\u5fc3\u7b4b\u3092\u4fdd\u8b77\u3057\u307e\u3059\u3002<br \/>\n\u3053\u308c\u3092\u3001\u865a\u8840\u30d7\u30ec\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30cb\u30f3\u30b0\u3068\u3044\u3044\u307e\u3059\u304c\u3001\u5fc3\u7b4b\u306eSUR2A\u306b\u89aa\u548c\u6027\u3092\u3082\u3064SU\u85ac\u306f\u5fc3\u7b4bK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306e\u958b\u53e3\u3092\u963b\u5bb3\u3057\u3001\u5fc3\u7b4b\u969c\u5bb3\u3092\u52a9\u9577\u3057\u3066\u3057\u307e\u3046\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u5b9f\u969b\u3001\u30b0\u30ea\u30d9\u30f3\u30af\u30e9\u30df\u30c9\u306f\u81b5\u81d3\u3068\u5fc3\u7b4b\u306eSUR\u306b\u5f37\u304f\u7d50\u5408\u3059\u308b\u305f\u3081\u3001\u72ed\u5fc3\u75c7\u3084\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u75c7\u4f8b\u3067\u306f\u4f7f\u7528\u3092\u63a7\u3048\u308b\u3079\u304d\u3068\u3044\u3046\u6307\u6458\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<h2><span id=\"SU\">SU\u85ac\u306e\u7a2e\u985e\u3068\u7279\u5fb4<\/span><\/h2>\n<p>SU\u85ac\u306f1956\u5e74\u306b\u7b2c\uff11\u4e16\u4ee3\u306e\u30c8\u30eb\u30d6\u30bf\u30df\u30c9\u304c\u767b\u5834\u3057\u3001\u305d\u306e\u5f8c\u30c8\u30eb\u30d6\u30bf\u30df\u30c9\u306b\u6bd4\u3079\u3066\u52b9\u529b\u6bd4\u304c200\u500d\uff5e400\u500d\u3082\u3042\u308b\u30b0\u30ea\u30d9\u30f3\u30af\u30e9\u30df\u30c9\u306a\u3069\u306e\u7b2c\uff12\u4e16\u4ee3\u306eSU\u85ac\u304c\u958b\u767a\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n\u73fe\u5728\u3067\u306f\u3001\u81b5\u81d3\u3060\u3051\u3067\u306a\u304f\u809d\u81d3\u3084\u9aa8\u683c\u7b4b\u306a\u3069\u306b\u3082\u4f5c\u7528\u3057\u3001\u5f37\u529b\u304b\u3064\u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u7b2c\uff13\u4e16\u4ee3\u306e\u30b0\u30ea\u30e1\u30d4\u30ea\u30c9\u304c\u591a\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\nSU\u85ac\u306e\u52b9\u679c\u306e\u9055\u3044\u306f\u3001\u81b5\u03b2\u7d30\u80de\u306eSUR\uff08\u30b9\u30eb\u30db\u30cb\u30eb\u5c3f\u7d20\u53d7\u5bb9\u4f53\uff09\u3078\u306e\u300c\u7d50\u5408\u529b\u306e\u5f37\u3055\u300d\u3084\u300c\u4ee3\u8b1d\u6642\u9593\uff08\u534a\u6e1b\u671f\uff09\u300d\u306e\u5dee\u306b\u3088\u308a\u6c7a\u5b9a\u3055\u308c\u307e\u3059\u3002<\/p>\n<h3><span id=\"SU-2\">\u7b2c\uff11\u4e16\u4ee3SU\u85ac<\/span><\/h3>\n<p>\u30fb\u30c8\u30eb\u30d6\u30bf\u30df\u30c9\uff08\u30e9\u30b9\u30c1\u30ce\u30f3\u00ae\uff09<br \/>\n\u534a\u6e1b\u671f\uff1a\uff15.\uff19\uff48\u3001\u4f5c\u7528\u6642\u9593\uff1a\uff16\uff5e\uff11\uff12\uff48\u3001\uff12\uff15\uff10\uff5e\uff11\uff15\uff10\uff10mg\/\u65e5<br \/>\n\u30fb\u30a2\u30bb\u30c8\u30d8\u30ad\u30b5\u30df\u30c9\uff08\u30b8\u30e1\u30ea\u30f3\u00ae\uff09<br \/>\n\u534a\u6e1b\u671f\uff1a\uff13.\uff12\uff48\u3001\u4f5c\u7528\u6642\u9593\uff1a\uff11\uff10\uff5e\uff11\uff12\uff48\u3001\uff12\uff15\uff10\uff5e\uff11\uff15\uff10\uff10mg\/\u65e5<br \/>\n\u30fb\u30af\u30ed\u30eb\u30d7\u30ed\u30d1\u30df\u30c9\uff08\u30a2\u30d9\u30de\u30a4\u30c9\u00ae\uff09<br \/>\n\u534a\u6e1b\u671f\uff1a\uff13\uff13\uff48\u3001\u4f5c\u7528\u6642\u9593\uff1a\uff12\uff14\uff5e\uff16\uff10\uff48\u3001\uff11\uff10\uff10\uff5e\uff15\uff10\uff10mg\/\u65e5<br \/>\n\u30fb\u30b0\u30ea\u30af\u30ed\u30d4\u30e9\u30df\u30c9\uff08\u30c7\u30a2\u30e1\u30ea\u30f3S\u00ae\uff09<br \/>\n\u534a\u6e1b\u671f\uff1ano data\u3001\u4f5c\u7528\u6642\u9593\uff1a\uff16\uff48\u3001\uff12\uff15\uff10\uff5e\uff15\uff10\uff10mg\/\u65e5<\/p>\n<h3><span id=\"SU-3\">\u7b2c\uff12\u4e16\u4ee3SU\u85ac<\/span><\/h3>\n<p>\u30fb\u30b0\u30ea\u30d6\u30be\u30fc\u30eb\uff08\u30b0\u30eb\u30c7\u30a2\u30fc\u30bc\u00ae\uff09<br \/>\n\u534a\u6e1b\u671f\uff1ano data\u3001\u4f5c\u7528\u6642\u9593\uff1a\uff11\uff12\uff5e\uff12\uff14\uff48\u3001\uff11\uff12\uff15\uff5e\uff15\uff10\uff10mg\/\u65e5<br \/>\n\u30fb\u30b0\u30ea\u30d9\u30f3\u30af\u30e9\u30df\u30c9\uff08\u30aa\u30a4\u30b0\u30eb\u30b3\u30f3\u00ae\u3001\u30c0\u30aa\u30cb\u30fc\u30eb\u00ae\uff09<br \/>\n\u534a\u6e1b\u671f\uff1a\uff12.\uff17\uff48\u3001\u4f5c\u7528\u6642\u9593\uff1a\uff11\uff12\uff5e\uff12\uff14\uff48\u3001\uff11.\uff12\uff15\uff5e\uff17.\uff15mg\/\u65e5<br \/>\n\u5fc3\u7b4b\u306eSUR2A\u306b\u3082\u5f37\u304f\u7d50\u5408\u3059\u308b\u305f\u3081\u3001\u72ed\u5fc3\u75c7\u3084\u5fc3\u7b4b\u6897\u585e\u306e\u60a3\u8005\u3067\u306f\u6b7b\u4ea1\u7387\u3092\u6709\u610f\u306b\u9ad8\u3081\u308b\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u30fb\u30b0\u30ea\u30af\u30e9\u30b8\u30c9\uff08\u30b0\u30ea\u30df\u30af\u30ed\u30f3\u00ae\uff09<br \/>\n\u534a\u6e1b\u671f\uff1a\uff16\uff5e\uff11\uff12\uff48\u3001\u4f5c\u7528\u6642\u9593\uff1a\uff16\uff5e\uff12\uff14\uff48\u3001\uff14\uff10\uff5e\uff11\uff12\uff10mg\/\u65e5<br \/>\n\u81b5\u03b2\u7d30\u80de\u306eSUR1\u3078\u306e\u9078\u629e\u7684\u304c\u9ad8\u3044\u85ac\u5264\u3067\u3059\u3002\u5fc3\u7b4b\u306eSUR2A\u3078\u306e\u89aa\u548c\u6027\u304c\u4f4e\u304f\u3001\u5fc3\u8840\u7ba1\u5408\u4f75\u75c7\u306e\u3042\u308b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u3082\u671b\u307e\u3057\u3044\u85ac\u5264\u3068\u3044\u308f\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u307e\u305f\u3001\u30d5\u30ea\u30fc\u30e9\u30b8\u30ab\u30eb\u6355\u6349\u306b\u3088\u308b\u8840\u5c0f\u677f\u51dd\u96c6\u6291\u5236\u4f5c\u7528\u3084\u6297\u9178\u5316\u4f5c\u7528\u3082\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u52d5\u8108\u786c\u5316\u306e\u6291\u5236\u52b9\u679c\u3082\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<h3><span id=\"SU-4\">\u7b2c\uff13\u4e16\u4ee3SU\u85ac<\/span><\/h3>\n<p>\u30fb\u30b0\u30ea\u30e1\u30d4\u30ea\u30c9\uff08\u30a2\u30de\u30ea\u30fc\u30eb\u00ae\uff09<br \/>\n\u534a\u6e1b\u671f\uff1a\uff11.\uff15\uff48\u3001\u4f5c\u7528\u6642\u9593\uff1a\uff16\uff5e\uff11\uff12\uff48\u3001\uff11\uff5e\uff16mg\/\u65e5<br \/>\n\u30b0\u30ea\u30d9\u30f3\u30af\u30e9\u30df\u30c9\u306b\u6bd4\u3079\u3066\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\u4f5c\u7528\u304c\u5f31\u304f\u3001\u6301\u7d9a\u6642\u9593\u304c\u77ed\u3044\u306e\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u540c\u7b49\u306e\u8840\u7cd6\u964d\u4e0b\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u305d\u306e\u7406\u7531\u3068\u3057\u3066\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u6539\u5584\u4f5c\u7528\u3092\u6709\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u63a8\u6e2c\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u809d\u81d3\u306e\u7cd6\u53d6\u308a\u8fbc\u307f\u306e\u4fc3\u9032\u3001\u7cd6\u653e\u51fa\u306e\u6291\u5236\u3001\u307e\u305f\u8102\u80aa\u7d30\u80de\u306b\u304a\u3051\u308b\u7cd6\u53d6\u308a\u8fbc\u307f\u306e\u4fc3\u9032\u306a\u3069\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3053\u308c\u3089\u3092\u81b5\u81d3\u4ee5\u5916\u306e\u81d3\u5668\u3078\u306e\u4f5c\u7528\u3068\u3044\u3046\u610f\u5473\u3067\u300c\u81b5\u5916\u4f5c\u7528\u300d\u3068\u3088\u3070\u308c\u3001\u3053\u308c\u306b\u3088\u308a\u4f4e\u8840\u7cd6\u304c\u5c11\u306a\u3044\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u826f\u597d\u306a\u8840\u7cd6\u7ba1\u7406\u304c\u5f97\u3089\u308c\u307e\u3059\u3002<br \/>\n\u5fc3\u7b4b\u306eSUR2A\u306b\u306f\u5f31\u3044\u89aa\u548c\u6027\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u30b0\u30ea\u30d9\u30f3\u30af\u30e9\u30df\u30c9\u3068\u7570\u306a\u308a\u5fc3\u7b4b\u7d30\u80de\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u819c\u306eK<sub><span style=\"font-size: small;\">ATP<\/span><\/sub>\u30c1\u30e3\u30cd\u30eb\u306b\u306f\u4f5c\u7528\u3057\u306a\u3044\u305f\u3081\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306f\u5c11\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<hr \/>\n<p>\u4ee5\u4e0a\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u6a5f\u69cb\u304b\u3089SU\u85ac\u306e\u4f5c\u7528\u6a5f\u5e8f\u3001\u5404\u85ac\u5264\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066\u307e\u3068\u3081\u307e\u3057\u305f\u3002<br \/>\n\u7686\u3055\u307e\u306e\u77e5\u8b58\u306e\u6574\u7406\u306b\u5f79\u7acb\u3066\u3070\u5e78\u3044\u3067\u3059\u3002<br \/>\n\u53c2\u8003\u3001\u56f3\u5f15\u7528\uff1a\u6708\u520a\u7cd6\u5c3f\u75c5 2009.7\uff08\u533b\u5b66\u51fa\u7248\uff09\u3001\u985e\u4f3c\u85ac\u306e\u4f7f\u3044\u5206\u3051\uff08\u7f8a\u571f\u793e\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7cd6\u5c3f\u75c5\u6027\u814e\u75c7\u306f\u7cd6\u5c3f\u75c5\u306b\u3064\u304d\u3082\u306e\u306e\u8840\u7cd6\u5024\u964d\u4e0b\u4fc3\u9032\u5264\u3067\u3059\u3002\u308f\u305f\u3057\u306f\u3001\u3053\u308c\u3067\u814e\u81d3\u6a5f\u80fd\u60aa &hellip; <a href=\"http:\/\/naosuzo-mystyle.com\/tounyoubyou\/?p=1897\">\u7d9a\u304d\u3092\u8aad\u3080 <span 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