{"id":1954,"date":"2017-01-24T05:39:49","date_gmt":"2017-01-23T20:39:49","guid":{"rendered":"http:\/\/naosuzo.net\/?p=1954"},"modified":"2017-01-24T05:39:49","modified_gmt":"2017-01-23T20:39:49","slug":"sglt2%e9%98%bb%e5%ae%b3%e8%96%ac%e3%81%a8%e9%a3%9f%e4%ba%8b%e7%99%82%e6%b3%95%e3%80%82%e7%97%a9%e3%81%9b%e7%b6%9a%e3%81%91%e3%82%8b%ef%bc%9f","status":"publish","type":"post","link":"http:\/\/naosuzo-mystyle.com\/seikatsu\/2017\/01\/24\/sglt2%e9%98%bb%e5%ae%b3%e8%96%ac%e3%81%a8%e9%a3%9f%e4%ba%8b%e7%99%82%e6%b3%95%e3%80%82%e7%97%a9%e3%81%9b%e7%b6%9a%e3%81%91%e3%82%8b%ef%bc%9f\/","title":{"rendered":"SGLT2\u963b\u5bb3\u85ac\u3068\u98df\u4e8b\u7642\u6cd5\u3002\u75e9\u305b\u7d9a\u3051\u308b\uff1f"},"content":{"rendered":"

\u30102014\/08\/12 \u3057\u3089\u306d\u306e\u305e\u308b\u3070
\n\u30e1\u30c7\u30a3\u30ab\u30eb\u671d\u65e5 2014\u5e748\u6708\u53f7
\n\u96d1\u8a8c\uff1a\u30e1\u30c7\u30a3\u30ab\u30eb\u671d\u65e5\u306e2014\u5e748\u6708\u53f7\u3092\u8aad\u3093\u3067\u3044\u305f\u3089\uff0c\u8208\u5473\u6df1\u3044\u8a18\u4e8b\u3092\u898b\u3064\u3051\u307e\u3057\u305f\uff0e
\n\u25c7\u8840\u4e2d\u30b1\u30c8\u30f3\u4f53\u6fc3\u5ea6\u304c\u4e0a\u6607\u3059\u308b\uff0e
\n\u25c7\u5c3f\u306b\u30b1\u30c8\u30f3\u4f53\u304c\u51fa\u308b\uff0e
\n\u25c7\u809d\u81d3\u7cd6\u65b0\u751f\u304c\u4ea2\u9032(\u6ce81)\u3057\u3066\u809d\u4e2d\u30b0\u30ea\u30b3\u30fc\u30b2\u30f3\u304c\u67af\u6e07\u3059\u308b\uff0e
\n\u305d\u306e\u7d50\u679c\uff1b
\n\u25c7\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u304c\u61f8\u5ff5\u3055\u308c\u308b
\n\u25c7\u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\uff0e
\n\u3053\u308c\uff0c\u7cd6\u8cea\u5236\u9650\u98df\u306b\u3064\u3044\u3066\u66f8\u304b\u308c\u305f\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\uff0e \u3053\u308c\u306f\u30e1\u30c7\u30a3\u30ab\u30eb\u671d\u65e5\u306e2014\u5e748\u6708\u53f7P.30\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u305f\uff0c\u300eSGLT2\u963b\u5bb3\u85ac\u3068\u98df\u4e8b\u7642\u6cd5\u300f\u3068\u3044\u3046\u8a18\u4e8b\u306e\u4e2d\u3067\uff0cSGLT2\u963b\u5bb3\u85ac\u306b\u3088\u308a\u767a\u751f\u3059\u308b\u554f\u984c\u70b9\u3068\u3057\u3066\u6319\u3052\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u3067\u3059\uff0e
\n(\u6ce81) SGLT2\u963b\u5bb3\u85ac\u306f\u809d\u81d3\u306e\u7cd6\u65b0\u751f\u3092\u4ea2\u9032\u3055\u305b\u308b
\nJ. Clin. Invest. Vol.124(2), 509-514, 2014
\n\u65e5\u672c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u306f\uff0c\u4e0a\u8a18\u3068\u307e\u3063\u305f\u304f\u540c\u3058\u7406\u7531\u3092\u3042\u3052\u3066\uff0c\u3053\u308c\u307e\u3067\u3055\u3093\u3056\u3093\u7cd6\u8cea\u5236\u9650\u98df\u306f\u5371\u967a\u3060\u3068\u3042\u3052\u3064\u3089\u3063\u3066\u304a\u304d\u306a\u304c\u3089\uff0cSGLT2\u963b\u5bb3\u85ac\u306b\u3064\u3044\u3066\u306f\uff0c\u5922\u306e\u3088\u3046\u306a\u7cd6\u5c3f\u75c5\u65b0\u85ac\u3060\u3068\u3082\u3066\u306f\u3084\u3057\u3066\u304d\u307e\u3057\u305f(\u6ce82)\uff0e
\n(\u6ce82)\u65e5\u7d4c\u30e1\u30c7\u30a3\u30ab\u30eb 2014\u5e743\u6708\u53f7 p.53
\n\u300e\u65b0\u3057\u3044\u4f5c\u7528\u6a5f\u5e8f\u3092\u6301\u3064SGLT2\u963b\u5bb3\u85ac\u306e\u767b\u5834\u3067(\u8840\u7cd6\u5024\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306e)\u76ee\u6a19\u9054\u6210\u7387\u304c\u3088\u308a\u9ad8\u307e\u308a\uff0c\u5c06\u6765\u7cd6\u5c3f\u75c5\u5408\u4f75\u75c7\u306b\u60a9\u3080\u60a3\u8005\u304c\u5c11\u3057\u3067\u3082\u6e1b\u308b\u3053\u3068\u3092\u671f\u5f85\u3057\u3066\u3044\u308b\u300f
\n\u6771\u5927\u75c5\u9662 \u9580\u8107\u9662\u9577 \u8ac7\uff1b
\n\u540c\u3058\u73fe\u8c61\u304c\u767a\u751f\u3059\u308b\u306e\u306b\uff0c\u4e00\u65b9\u3067\u7cd6\u8cea\u5236\u9650\u98df\u306f\u5371\u967a\u3068\u8a00\u3044\uff0c\u4ed6\u65b9\u3067SGLT2\u963b\u5bb3\u85ac\u306e\u65b9\u306f\u300e\u6709\u671b\u306a\u7cd6\u5c3f\u75c5\u6cbb\u7642\u624b\u6bb5\u300f\u3068\u6301\u3061\u4e0a\u3052\u308b\u306e\u306f\uff0c\u77db\u76fe\u3057\u3066\u3044\u307e\u3059\uff0e
\n\u3057\u304b\u3082\u5091\u4f5c\u306a\u306e\u306f\uff0c\u3053\u306e\u8a18\u4e8b\u306e\u8da3\u65e8\u304c\u307e\u3063\u305f\u304f\u66d6\u6627\u306a\u70b9\u3067\u3059\uff0e\u3053\u306e\u300eSGLT2\u963b\u5bb3\u85ac\u3068\u98df\u4e8b\u7642\u6cd5\u300f\u3068\u3044\u3046\u8a18\u4e8b\u3092\u4f55\u5ea6\u3082\u8aad\u307f\u8fd4\u3057\u307e\u3057\u305f\u304c\uff0c\u7d50\u8ad6\u3089\u3057\u304d\u3082\u306e\u306f\u898b\u5f53\u305f\u3089\u305a\uff0c\u8981\u3059\u308b\u306b\u4f55\u3092\u8a00\u3044\u305f\u3044\u306e\u304b\u3055\u3063\u3071\u308a\u308f\u304b\u3089\u306a\u3044\u306e\u3067\u3059\uff0e
\n\u540c\u8a8c\u306e\u5225\u306e\u7b87\u6240(p.25)\u306b\u306f\uff0c\u300eSGLT2\u963b\u5bb3\u85ac\u3092\u670d\u7528\u3059\u308b\u3068\uff0c1\u65e5\u3042\u305f\u308a\u304a\u3088\u305d400kcal\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u306b\u76f8\u5f53\u3059\u308b\u7cd6\u8cea\u304c\u5c3f\u304b\u3089\u6392\u6cc4\u3055\u308c\u308b\u300f\u3068\u3042\u308a\u307e\u3059\uff0e
\n\u305d\u3053\u30671600kcal(\u5185 \u7cd6\u8cea\u306f60%=960kcal)\u306e\u3044\u308f\u3086\u308b\u300e\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u98df\u300f\u3092\u6442\u3063\u3066\u3044\u308b\u3068\uff0c\u305f\u3060\u3067\u3055\u3048\uff0c\u30ae\u30ea\u30ae\u30ea\u306e\u6700\u4f4e\u30ab\u30ed\u30ea\u30fc\u306b\u8a2d\u5b9a\u3055\u308c\u3066\u3044\u308b\u306e\u306b\uff0c\u66f4\u306b400kcal\u307b\u3069\u30ab\u30ed\u30ea\u30fc\u6442\u53d6\u4e0d\u8db3\u306b\u306a\u308a\u307e\u3059\uff0e\u3053\u306e\u4e0d\u8db3\u5206\u3092\u4f55\u306b\u3088\u3063\u3066\u3069\u308c\u304f\u3089\u3044\u88dc\u3046\u3079\u304d\u306a\u306e\u304b\uff0c\u3053\u306e\u8a18\u4e8b\u3067\u306f\u4e00\u5207\u89e6\u308c\u3066\u3044\u306a\u3044\u306e\u3067\u3059\uff0e
\n\u8a18\u4e8b\u4e2d\u3067\u306f\uff0c\u300eSGLT2\u963b\u5bb3\u85ac\u306b\u3088\u308a\u7cd6\u6392\u6cc4\u3092\u4fc3\u9032\u3059\u308b\u4e00\u65b9\u3067\uff0c\u7cd6\u8cea\u6442\u53d6\u91cf\u3092\u5897\u52a0\u3059\u308b\u3088\u3046\u306a\u98df\u4e8b\u7642\u6cd5\u306f\uff0c\u7cd6\u5c3f\u75c5\u6cbb\u7642\u3068\u3057\u3066\u672c\u672b\u8ee2\u5012\u3067\u3042\u308b\u300f\u3068\u3082\u66f8\u304b\u308c\u3066\u3044\u307e\u3059(p.31)\uff0e
\n\u3064\u307e\u308a\uff0c\u4e0d\u8db3\u3059\u308b\u30ab\u30ed\u30ea\u30fc\u3092\u7cd6\u8cea\u3067\u88dc\u3063\u3066\u306f\u3044\u3051\u306a\u3044\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\uff0e
\n\u3068\u3053\u308d\u304c\u3053\u306e\u8a18\u4e8b\u3067\u306f\u7d9a\u3051\u3066\uff0c\u300eSGLT2\u963b\u5bb3\u85ac\u670d\u7528\u60a3\u8005\u304c\u7cd6\u8cea\u5236\u9650\u98df\u3092\u884c\u3063\u305f\u5834\u5408\u306b\u306f\uff0c\u7d76\u5bfe\u7684\u306a\u7cd6\u4e0d\u8db3\u306b\u9665\u308b\u300f\u3068\u3042\u308a\uff0c\u3064\u307e\u308a\u306f\u7cd6\u8cea\u306f\u3075\u3084\u3057\u3066\u306f\u306a\u3089\u306a\u3044\u304c\uff0c\u306a\u304a\u304b\u3064\u8102\u8cea\u3082\u86cb\u767d\u8cea\u3082\u5897\u3084\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u3068\u3044\u3046\u308f\u3051\u3067\u3059\uff0e
\n\u306a\u3089\u3070\uff0c\u3044\u3063\u305f\u3044\u3053\u306e\u30ab\u30ed\u30ea\u30fc\u4e0d\u8db3\u3092\u3069\u3046\u305b\u3088\u3068\u3044\u3046\u306e\u3067\u3057\u3087\u3046\u304b\uff1f
\n\u3053\u306e\u8a18\u4e8b\u3067\u306f\u305d\u306e\u70b9\u306f\uff0c\u6700\u5f8c\u306b\u300e\u73fe\u6642\u70b9\u3067\u306fSGLT2\u963b\u5bb3\u85ac\u306b\u5bfe\u3059\u308b\u9069\u5207\u306a\u98df\u4e8b\u7642\u6cd5\u306f\u660e\u3089\u304b\u3067\u306a\u3044\u300f\u3068\u7d50\u8ad6\u4e0d\u660e\u306b\u3057\u3066\u3044\u307e\u3059\uff0e\u5bdf\u3059\u308b\u306b\uff0c\u4eca\u307e\u3067\u300e\u9ad8\u86cb\u767d\u30fb\u9ad8\u8102\u8cea\u306e\u7cd6\u8cea\u5236\u9650\u306f\u5371\u967a\u300f\u3068\u8a00\u3044\u7d9a\u3051\u3066\u304d\u305f\u624b\u524d\uff0c\u81ea\u7e04\u81ea\u7e1b\u306b\u9665\u3063\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\uff0e
\n\u9069\u5207\u306a\u98df\u4e8b\u7642\u6cd5\u304c\u5b9a\u307e\u3089\u306a\u3044\u306e\u306a\u3089\uff0cSGLT2\u963b\u5bb3\u85ac\u3092\u60a3\u8005\u306b\u51e6\u65b9\u3057\u305f\u533b\u5e2b\u306f\uff0c\u98df\u4e8b\u306b\u3064\u3044\u3066\u4f55\u3082\u6ce8\u610f\u559a\u8d77\u3057\u306a\u304f\u3066\u3082\u3044\u3044\u306e\u3067\u3057\u3087\u3046\u304b\uff1f \u7ba1\u7406\u6804\u990a\u58eb\u306f\uff0c\u3053\u308c\u307e\u3067\u901a\u308a\u306e\u300e\u9ad8\u7cd6\u8cea \u7cd6\u5c3f\u75c5\u6a19\u6e96\u98df\u300f\u3092\u305d\u306e\u307e\u307e\u7d9a\u3051\u308d\u3068\u8a00\u3063\u3066\u3044\u3044\u3082\u306e\u3067\u3057\u3087\u3046\u304b\uff1f \u3053\u306e\u8a18\u4e8b\u3092\u8aad\u3093\u3060\u60a3\u8005\u306f\u3044\u3063\u305f\u3044\u4f55\u3092\u3069\u3046\u3057\u305f\u3089\u3044\u3044\u306e\u3067\u3057\u3087\u3046\u304b\uff1f
\n\u305f\u3057\u304b\u306bBMI\u304c30\u3092\u8d85\u3048\u308b\u3088\u3046\u306a\u8d85\u80a5\u6e80\u306e\u60a3\u8005\u306a\u3089\uff0c\u305d\u308c\u3067\u6025\u901f\u306b\u75e9\u305b\u3089\u308c\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\uff0c1,600kcal\u306e\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u98df\u3067\u3055\u3048\u8f9b\u3044\u3068\u601d\u3063\u3066\u3044\u308b\u4eba\u304c\uff0c\u66f4\u306b400kcal\u306e\u30ab\u30ed\u30ea\u30fc\u5207\u308a\u6368\u3066\u306b\u8010\u3048\u3089\u308c\u308b\u3067\u3057\u3087\u3046\u304b\uff1f\u4ee5\u524dNHK\u3067\u653e\u6620\u3055\u308c\u305f\u4eba\u306e\u3088\u3046\u306b\uff0c\u30d5\u30e9\u30d5\u30e9\u306b\u306a\u3063\u3066\u968e\u6bb5\u3082\u767b\u308c\u306a\u304f\u306a\u308b\u3067\u3057\u3087\u3046\uff0e\u679c\u305f\u3057\u3066\u305d\u308c\u304c\u300e\u6709\u671b\u306a\u7cd6\u5c3f\u75c5\u6cbb\u7642\u624b\u6bb5\u300f\u3068\u3044\u3048\u308b\u3067\u3057\u3087\u3046\u304b\uff1f
\n\u7d50\u5c40\uff0c\u9ad8\u7cd6\u8cea\u30fb\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u98df\u3092\u6307\u793a\u3055\u308c\u3066\u3044\u308b\u60a3\u8005\u306b\uff0cSGLT2\u963b\u5bb3\u85ac\u304c\u6295\u4e0e\u3055\u308c\u305f\u3089\uff0c400kcal\u5206\u306e\u7cd6\u8cea\u304c\u6442\u53d6\u3055\u308c\u306a\u304b\u3063\u305f\u306e\u3068\u540c\u3058\u3067\u3059\u304b\u3089\uff0c\u3064\u307e\u308a\u306f\u305d\u308c\u306f\u3010\u5727\u5012\u7684\u306b\u30ab\u30ed\u30ea\u30fc\u4e0d\u8db3\uff0c\u304b\u3064\u4e2d\u9014\u534a\u7aef\u306a\u7cd6\u8cea\u5236\u9650\u98df\u3011\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059(\u6ce83)\uff0e \u3067\u3042\u308b\u306a\u3089\uff0c\u6700\u521d\u304b\u3089\u3010\u9069\u5207\u306a\u30ab\u30ed\u30ea\u30fc\u3067\u306e\u7cd6\u8cea\u5236\u9650\u98df\u3011\u306e\u65b9\u304c\u3088\u307b\u3069\u5b89\u5168\u3067\u3059\uff0e\u5c11\u306a\u304f\u3068\u3082\u7cd6\u8cea\u5236\u9650\u98df\u306f\uff0c\u5c3f\u8def\u30fb\u6027\u5668\u611f\u67d3\u75c7\u306f\u8d77\u3053\u3057\u305f\u308a\u3057\u307e\u305b\u3093\u304b\u3089\u306d\uff0e
\n(\u6ce83)
\n1600kcal\u306e\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u98df\u304c\uff0c\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u306e\u5968\u3081\u308b\u300e\u9069\u6b63\u30ab\u30ed\u30ea\u30fc\u6bd4\u300f\u3060\u3068\u3057\u305f\u5834\u5408\uff1b
\n\u70ad\u6c34\u5316\u7269\uff1a 60% = 960kcal
\n\u8102\u8cea\uff1a20% = 320kcal
\n\u86cb\u767d\u8cea\uff1a20% = 320kcal
\n\u5408\u8a08 1,600kcal
\n\u3053\u306e\u98df\u4e8b\u3092\u3057\u3066\u3044\u308b\u60a3\u8005\u304c\uff0cSGLT2\u963b\u5bb3\u85ac\u3092\u670d\u7528\u3057\u3066400kcal\u306e\u7cd6\u8cea\u304c\u6392\u6cc4\u3055\u308c\u308b\u3068\uff1b
\n\u70ad\u6c34\u5316\u7269\uff1a 960kcal – 400kcal = 560Kcal \u2190 47%
\n\u8102\u8cea\uff1a 320kcal \u2190 27%
\n\u86cb\u767d\u8cea:\uff1a 320kcal \u2190 27%
\n\u5408\u8a08\uff1a 1,200kcal
\n\u3064\u307e\u308a\uff0c\u70ad\u6c34\u5316\u7269\u304c50%\u672a\u6e80\u306b\u306a\u308b\u306e\u3067\uff0c\u300e50\uff5e60%\u306e\u70ad\u6c34\u5316\u7269\u304c\u9069\u6b63\u300f\u3068\u3059\u308b\u7cd6\u5c3f\u75c5\u5b66\u4f1a\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u304b\u3089\u5916\u308c\u3066\u3057\u307e\u3044\u307e\u3059\uff0e\u3011
\n
\n\u3057\u3089\u306d\u306e\u305e\u308b\u3070\u3000\u3055\u3093
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